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Fast Association and Slow Transitions in the Interaction between Two Intrinsically Disordered Protein Domains
Proteins that contain long disordered regions are prevalent in the proteome and frequently associated with diseases. However, the mechanisms by which such intrinsically disordered proteins (IDPs) recognize their targets are not well understood. Here, we report the first experimental investigation of...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464538/ https://ncbi.nlm.nih.gov/pubmed/22915588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.399436 |
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