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Fast Association and Slow Transitions in the Interaction between Two Intrinsically Disordered Protein Domains

Proteins that contain long disordered regions are prevalent in the proteome and frequently associated with diseases. However, the mechanisms by which such intrinsically disordered proteins (IDPs) recognize their targets are not well understood. Here, we report the first experimental investigation of...

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Detalhes bibliográficos
Main Authors: Dogan, Jakob, Schmidt, Tanja, Mu, Xin, Engström, Åke, Jemth, Per
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464538/
https://ncbi.nlm.nih.gov/pubmed/22915588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.399436
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