Fast Association and Slow Transitions in the Interaction between Two Intrinsically Disordered Protein Domains

Proteins that contain long disordered regions are prevalent in the proteome and frequently associated with diseases. However, the mechanisms by which such intrinsically disordered proteins (IDPs) recognize their targets are not well understood. Here, we report the first experimental investigation of...

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Bibliografiske detaljer
Main Authors: Dogan, Jakob, Schmidt, Tanja, Mu, Xin, Engström, Åke, Jemth, Per
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464538/
https://ncbi.nlm.nih.gov/pubmed/22915588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.399436
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