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P2X7 Receptor is Involved in Mitochondrial Dysfunction Induced by Extracellular Alpha Synuclein in Neuroblastoma SH-SY5Y Cells

The purinergic P2X7 receptor (P2X7R) belongs to a family of trimeric ion channels that are gated by extracellular adenosine 5′-triphosphate (ATP). Several studies have pointed to a role of P2X7R-dependent signalling in Parkinson's disease (PD)-related neurodegeneration. The pathology of (PD) is...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Wilkaniec, Anna, Cieślik, Magdalena, Murawska, Emilia, Babiec, Lidia, Gąssowska-Dobrowolska, Magdalena, Pałasz, Ewelina, Jęśko, Henryk, Adamczyk, Agata
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312811/
https://ncbi.nlm.nih.gov/pubmed/32486485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21113959
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