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P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells

Abnormalities of alpha-synuclein (ASN), the main component of protein deposits (Lewy bodies), were observed in Parkinson’s disease (PD), dementia with Lewy bodies, Alzheimer’s disease, and other neurodegenerative disorders. These alterations include increase in the levels of soluble ASN oligomers in...

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Detalhes bibliográficos
Publicado no:Purinergic Signal
Main Authors: Wilkaniec, Anna, Gąssowska, Magdalena, Czapski, Grzegorz A., Cieślik, Magdalena, Sulkowski, Grzegorz, Adamczyk, Agata
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563296/
https://ncbi.nlm.nih.gov/pubmed/28516276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-017-9567-2
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