P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells

Abnormalities of alpha-synuclein (ASN), the main component of protein deposits (Lewy bodies), were observed in Parkinson’s disease (PD), dementia with Lewy bodies, Alzheimer’s disease, and other neurodegenerative disorders. These alterations include increase in the levels of soluble ASN oligomers in...

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Publicat a:Purinergic Signal
Autors principals: Wilkaniec, Anna, Gąssowska, Magdalena, Czapski, Grzegorz A., Cieślik, Magdalena, Sulkowski, Grzegorz, Adamczyk, Agata
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563296/
https://ncbi.nlm.nih.gov/pubmed/28516276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-017-9567-2
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