P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells

Abnormalities of alpha-synuclein (ASN), the main component of protein deposits (Lewy bodies), were observed in Parkinson’s disease (PD), dementia with Lewy bodies, Alzheimer’s disease, and other neurodegenerative disorders. These alterations include increase in the levels of soluble ASN oligomers in...

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Publicado en:Purinergic Signal
Main Authors: Wilkaniec, Anna, Gąssowska, Magdalena, Czapski, Grzegorz A., Cieślik, Magdalena, Sulkowski, Grzegorz, Adamczyk, Agata
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563296/
https://ncbi.nlm.nih.gov/pubmed/28516276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-017-9567-2
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