The Dual-Active Histamine H(3) Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice

The histamine H3 receptor (H3R) functions as auto- and hetero-receptors, regulating the release of brain histamine (HA) and acetylcholine (ACh), respectively. The enzyme acetylcholine esterase (AChE) is involved in the metabolism of brain ACh. Both brain HA and ACh are implicated in several cognitiv...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Eissa, Nermin, Azimullah, Sheikh, Jayaprakash, Petrilla, Jayaraj, Richard L., Reiner, David, Ojha, Shreesh K., Beiram, Rami, Stark, Holger, Łażewska, Dorota, Kieć-Kononowicz, Katarzyna, Sadek, Bassem
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312782/
https://ncbi.nlm.nih.gov/pubmed/32503208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21113996
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