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The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism

Autistic spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairment in social communication and restricted/repetitive behavior patterns or interests. Antagonists targeting histamine H3 receptor (H3R) are considered potential therapeutic agents for the therapeutic management...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Eissa, Nermin, Jayaprakash, Petrilla, Azimullah, Sheikh, Ojha, Shreesh K., Al-Houqani, Mohammed, Jalal, Fakhreya Y., Łażewska, Dorota, Kieć-Kononowicz, Katarzyna, Sadek, Bassem
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117350/
https://ncbi.nlm.nih.gov/pubmed/30166610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31385-7
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