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Simultaneous Blockade of Histamine H(3) Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism

Autism spectrum disorder (ASD) is a heterogenous neurodevelopmental disorder defined by persistent deficits in social interaction and the presence of patterns of repetitive and restricted behaviors. The central neurotransmitters histamine (HA) and acetylcholine (ACh) play pleiotropic roles in physio...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Eissa, Nermin, Jayaprakash, Petrilla, Stark, Holger, Łażewska, Dorota, Kieć-Kononowicz, Katarzyna, Sadek, Bassem
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563744/
https://ncbi.nlm.nih.gov/pubmed/32872194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10091251
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