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The Histamine H3 Receptor Antagonist E159 Reverses Memory Deficits Induced by Dizocilpine in Passive Avoidance and Novel Object Recognition Paradigm in Rats

The involvement of histamine H3 receptors (H3Rs) in memory is well known, and the potential of H3R antagonists in therapeutic management of neuropsychiatric diseases, e.g., Alzheimer disease (AD) is well established. Therefore, the effects of histamine H3 receptor (H3R) antagonist E159 (2.5–10 mg/kg...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Alachkar, Alaa, Łażewska, Dorota, Kieć-Kononowicz, Katarzyna, Sadek, Bassem
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643952/
https://ncbi.nlm.nih.gov/pubmed/29075190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00709
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