The Histamine H3 Receptor Antagonist E159 Reverses Memory Deficits Induced by Dizocilpine in Passive Avoidance and Novel Object Recognition Paradigm in Rats

The involvement of histamine H3 receptors (H3Rs) in memory is well known, and the potential of H3R antagonists in therapeutic management of neuropsychiatric diseases, e.g., Alzheimer disease (AD) is well established. Therefore, the effects of histamine H3 receptor (H3R) antagonist E159 (2.5–10 mg/kg...

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發表在:Front Pharmacol
Main Authors: Alachkar, Alaa, Łażewska, Dorota, Kieć-Kononowicz, Katarzyna, Sadek, Bassem
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
主題:
Pharmacology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643952/
https://ncbi.nlm.nih.gov/pubmed/29075190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00709
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