The Dual-Active Histamine H(3) Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice

The histamine H3 receptor (H3R) functions as auto- and hetero-receptors, regulating the release of brain histamine (HA) and acetylcholine (ACh), respectively. The enzyme acetylcholine esterase (AChE) is involved in the metabolism of brain ACh. Both brain HA and ACh are implicated in several cognitiv...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Eissa, Nermin, Azimullah, Sheikh, Jayaprakash, Petrilla, Jayaraj, Richard L., Reiner, David, Ojha, Shreesh K., Beiram, Rami, Stark, Holger, Łażewska, Dorota, Kieć-Kononowicz, Katarzyna, Sadek, Bassem
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312782/
https://ncbi.nlm.nih.gov/pubmed/32503208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21113996
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