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Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC

The Legionella pneumophila effector MavC is a transglutaminase that carries out atypical ubiquitination of the host ubiquitin (Ub)‐conjugation enzyme UBE2N by catalyzing the formation of an isopeptide bond between Gln40(Ub) and Lys92(UBE2N), which leads to inhibition of signaling in the NF‐κB pathwa...

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Detalles Bibliográficos
Publicado en:Adv Sci (Weinh)
Main Authors: Guan, Hongxin, Fu, Jiaqi, Yu, Ting, Wang, Zhao‐Xi, Gan, Ninghai, Huang, Yini, Perčulija, Vanja, Li, Yu, Luo, Zhao‐Qing, Ouyang, Songying
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312448/
https://ncbi.nlm.nih.gov/pubmed/32596129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202000871
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