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Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC
The Legionella pneumophila effector MavC is a transglutaminase that carries out atypical ubiquitination of the host ubiquitin (Ub)‐conjugation enzyme UBE2N by catalyzing the formation of an isopeptide bond between Gln40(Ub) and Lys92(UBE2N), which leads to inhibition of signaling in the NF‐κB pathwa...
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| Publié dans: | Adv Sci (Weinh) |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7312448/ https://ncbi.nlm.nih.gov/pubmed/32596129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202000871 |
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