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Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC
The Legionella pneumophila effector MavC is a transglutaminase that carries out atypical ubiquitination of the host ubiquitin (Ub)‐conjugation enzyme UBE2N by catalyzing the formation of an isopeptide bond between Gln40(Ub) and Lys92(UBE2N), which leads to inhibition of signaling in the NF‐κB pathwa...
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| Опубликовано в: : | Adv Sci (Weinh) |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7312448/ https://ncbi.nlm.nih.gov/pubmed/32596129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202000871 |
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