MicroRNA regulation postbleomycin due to the R213G extracellular superoxide dismutase variant is predicted to suppress inflammatory and immune pathways

Oxidative stress is a key contributor to the development of dysregulated inflammation in acute lung injury (ALI). A naturally occurring single nucleotide polymorphism in the key extracellular antioxidant enzyme, extracellular superoxide dismutase (EC-SOD), results in an arginine to glycine substitut...

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Pubblicato in:Physiol Genomics
Autori principali: Ohlstrom, Denis, Hernandez-Lagunas, Laura, Garcia, Anastacia M., Allawzi, Ayed, Karimpour-Fard, Anis, Sucharov, Carmen C., Nozik-Grayck, Eva
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311677/
https://ncbi.nlm.nih.gov/pubmed/32421439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00116.2019
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