R213G polymorphism in SOD3 protects against bleomycin-induced inflammation and attenuates induction of proinflammatory pathways

Extracellular superoxide dismutase (EC-SOD), one of three mammalian SOD isoforms, is the sole extracellular enzymatic defense against superoxide. A known human single nucleotide polymorphism (SNP) in the matrix-binding domain of EC-SOD characterized by an arginine-to-glycine substitution at position...

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Dettagli Bibliografici
Pubblicato in:Physiol Genomics
Autori principali: Garcia, Anastacia M., Allawzi, Ayed, Tatman, Philip, Hernandez-Lagunas, Laura, Swain, Kalin, Mouradian, Gary, Bowler, Russell, Karimpour-Fard, Anis, Sucharov, Carmen C., Nozik-Grayck, Eva
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172610/
https://ncbi.nlm.nih.gov/pubmed/30004839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00053.2018
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