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CAR-T Cells Hit the Tumor Microenvironment: Strategies to Overcome Tumor Escape
Chimeric antigen receptor (CAR) T cell therapies have demonstrated remarkable efficacy for the treatment of hematological malignancies. However, in patients with solid tumors, objective responses to CAR-T cell therapy remain sporadic and transient. A major obstacle for CAR-T cells is the intrinsic a...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7311654/ https://ncbi.nlm.nih.gov/pubmed/32625204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01109 |
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