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CAR-T Cells and Oncolytic Viruses: Joining Forces to Overcome the Solid Tumor Challenge

Adoptive transfer of chimeric antigen receptor (CAR)-modified T cells has resulted in unprecedented rates of long-lasting complete responses in patients with leukemia and lymphoma. However, despite the impressive results in patients with hematologic malignancies, CAR-T cells have showed limited effe...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Guedan, Sonia, Alemany, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207052/
https://ncbi.nlm.nih.gov/pubmed/30405639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02460
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