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CAR T Cells for Solid Tumors: New Strategies for Finding, Infiltrating, and Surviving in the Tumor Microenvironment

Chimeric antigen receptor (CAR) T cells, T cells that have been genetically engineered to express a receptor that recognizes a specific antigen, have given rise to breakthroughs in treating hematological malignancies. However, their success in treating solid tumors has been limited. The unique chall...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Martinez, Marina, Moon, Edmund Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370640/
https://ncbi.nlm.nih.gov/pubmed/30804938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00128
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