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The mutREAD method detects mutational signatures from low quantities of cancer DNA

Mutational processes acting on cancer genomes can be traced by investigating mutational signatures. Because high sequencing costs limit current studies to small numbers of good-quality samples, we propose a robust, cost- and time-effective method, called mutREAD, to detect mutational signatures from...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Perner, Juliane, Abbas, Sujath, Nowicki-Osuch, Karol, Devonshire, Ginny, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311535/
https://ncbi.nlm.nih.gov/pubmed/32576827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16974-3
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