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MutSignatures: an R package for extraction and analysis of cancer mutational signatures

Cancer cells accumulate somatic mutations as result of DNA damage, inaccurate repair and other mechanisms. Different genetic instability processes result in characteristic non-random patterns of DNA mutations, also known as mutational signatures. We developed mutSignatures, an integrated R-based com...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Fantini, Damiano, Vidimar, Vania, Yu, Yanni, Condello, Salvatore, Meeks, Joshua J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589488/
https://ncbi.nlm.nih.gov/pubmed/33106540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75062-0
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