APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response

APOBEC enzymes are responsible for a mutation signature (TCW>T/G) implicated in a wide variety of tumors. We explore the APOBEC mutational signature in bladder cancer and the relationship with specific mutations, molecular subtype, gene expression, and survival using sequencing data from The Canc...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Glaser, Alexander P., Fantini, Damiano, Wang, Yiduo, Yu, Yanni, Rimar, Kalen J., Podojil, Joseph R., Miller, Stephen D., Meeks, Joshua J.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796993/
https://ncbi.nlm.nih.gov/pubmed/29435122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23344
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