APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response

APOBEC enzymes are responsible for a mutation signature (TCW>T/G) implicated in a wide variety of tumors. We explore the APOBEC mutational signature in bladder cancer and the relationship with specific mutations, molecular subtype, gene expression, and survival using sequencing data from The Canc...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Glaser, Alexander P., Fantini, Damiano, Wang, Yiduo, Yu, Yanni, Rimar, Kalen J., Podojil, Joseph R., Miller, Stephen D., Meeks, Joshua J.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796993/
https://ncbi.nlm.nih.gov/pubmed/29435122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23344
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