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Diaphanous-related formin mDia2 regulates beta2 integrins to control hematopoietic stem and progenitor cell engraftment

Bone marrow engraftment of the hematopoietic stem and progenitor cells (HSPCs) involves homing to the vasculatures and lodgment to their niches. How HSPCs transmigrate from the vasculature to the niches is unclear. Here, we show that loss of diaphanous-related formin mDia2 leads to impaired engraftm...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mei, Yang, Han, Xu, Liu, Yijie, Yang, Jing, Sumagin, Ronen, Ji, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311390/
https://ncbi.nlm.nih.gov/pubmed/32576838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16911-4
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