Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2)

The tumor microenvironment (TME) promotes tumor cell invasion and metastasis. An important step in the shift to a pro-cancerous microenvironment is the transformation of normal stromal fibroblasts to carcinoma-associated fibroblasts (CAFs). CAFs are present in a majority of solid tumors and can dire...

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Veröffentlicht in:PLoS One
Hauptverfasser: Dvorak, Kaitlyn M., Pettee, Krista M., Rubinic-Minotti, Kaitlin, Su, Robin, Nestor-Kalinoski, Andrea, Eisenmann, Kathryn M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875872/
https://ncbi.nlm.nih.gov/pubmed/29596520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195278
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