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Diaphanous-related formin mDia2 regulates beta2 integrins to control hematopoietic stem and progenitor cell engraftment

Bone marrow engraftment of the hematopoietic stem and progenitor cells (HSPCs) involves homing to the vasculatures and lodgment to their niches. How HSPCs transmigrate from the vasculature to the niches is unclear. Here, we show that loss of diaphanous-related formin mDia2 leads to impaired engraftm...

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Vydáno v:Nat Commun
Hlavní autoři: Mei, Yang, Han, Xu, Liu, Yijie, Yang, Jing, Sumagin, Ronen, Ji, Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311390/
https://ncbi.nlm.nih.gov/pubmed/32576838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16911-4
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