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Diaphanous-related formin mDia2 regulates beta2 integrins to control hematopoietic stem and progenitor cell engraftment

Bone marrow engraftment of the hematopoietic stem and progenitor cells (HSPCs) involves homing to the vasculatures and lodgment to their niches. How HSPCs transmigrate from the vasculature to the niches is unclear. Here, we show that loss of diaphanous-related formin mDia2 leads to impaired engraftm...

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Pubblicato in:Nat Commun
Autori principali: Mei, Yang, Han, Xu, Liu, Yijie, Yang, Jing, Sumagin, Ronen, Ji, Peng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311390/
https://ncbi.nlm.nih.gov/pubmed/32576838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16911-4
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