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Diaphanous-related formin mDia2 regulates beta2 integrins to control hematopoietic stem and progenitor cell engraftment

Bone marrow engraftment of the hematopoietic stem and progenitor cells (HSPCs) involves homing to the vasculatures and lodgment to their niches. How HSPCs transmigrate from the vasculature to the niches is unclear. Here, we show that loss of diaphanous-related formin mDia2 leads to impaired engraftm...

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Publicado en:Nat Commun
Autores principales: Mei, Yang, Han, Xu, Liu, Yijie, Yang, Jing, Sumagin, Ronen, Ji, Peng
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311390/
https://ncbi.nlm.nih.gov/pubmed/32576838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16911-4
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