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Tracing self-reactive B cells in normal mice

BCR transgenic mice dominate studies of B-cell tolerance; consequently, tolerance in normal mice expressing diverse sets of autoreactive B cells is poorly characterized. We have used single B-cell cultures to trace self-reactivity in BCR repertoires across the first and second tolerance checkpoints...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Nojima, Takuya, Reynolds, Alexander E., Kitamura, Daisuke, Kelsoe, Garnett, Kuraoka, Masayuki
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311292/
https://ncbi.nlm.nih.gov/pubmed/32414809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901015
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