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Tracing self-reactive B cells in normal mice

BCR transgenic mice dominate studies of B-cell tolerance; consequently, tolerance in normal mice expressing diverse sets of autoreactive B cells is poorly characterized. We have used single B-cell cultures to trace self-reactivity in BCR repertoires across the first and second tolerance checkpoints...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Nojima, Takuya, Reynolds, Alexander E., Kitamura, Daisuke, Kelsoe, Garnett, Kuraoka, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311292/
https://ncbi.nlm.nih.gov/pubmed/32414809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901015
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