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Natural IgM is Produced by CD5(−) Plasma Cells that Occupy a Distinct Survival Niche in Bone Marrow

Natural IgM is constitutively present in the serum, where it aids in the early control of viral and bacterial expansion. Natural IgM also plays a significant role in the prevention of autoimmune disease by promoting the clearance of cellular debris. Nevertheless, the origins of natural IgM have not...

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Vydáno v:J Immunol
Hlavní autoři: Reynolds, Alexander E., Kuraoka, Masayuki, Kelsoe, Garnett
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272881/
https://ncbi.nlm.nih.gov/pubmed/25429072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401203
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