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Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes
Dynamic trafficking of G protein-coupled receptors (GPCRs) out of cilia is mediated by the BBSome. In concert with its membrane recruitment factor, the small GTPase ARL6/BBS3, the BBSome ferries GPCRs across the transition zone, a diffusion barrier at the base of cilia. Here, we present the near-ato...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7311171/ https://ncbi.nlm.nih.gov/pubmed/32510327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55954 |
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