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BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone
A diffusion barrier at the transition zone enables the compartmentalization of signaling molecules by cilia. The BBSome and the small guanosine triphosphatase Arl6, which triggers BBSome coat polymerization, are required for the exit of activated signaling receptors from cilia, but how diffusion bar...
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| Published in: | J Cell Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Rockefeller University Press
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940304/ https://ncbi.nlm.nih.gov/pubmed/29483145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201709041 |
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