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Structural Basis for Membrane Targeting of the BBSome by ARL6

The BBSome is a coat-like ciliary trafficking complex composed of proteins mutated in Bardet-Biedl syndrome (BBS). A critical step in BBSome-mediated sorting is recruitment of the BBSome to membranes by the GTP–bound Arf-like GTPase ARL6. We have determined crystal structures of C. reinhardtii ARL6–...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Mourão, André, Nager, Andrew R., Nachury, Maxence V., Lorentzen, Esben
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255524/
https://ncbi.nlm.nih.gov/pubmed/25402481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2920
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