The Intraflagellar Transport Protein IFT27 Promotes BBSome Exit from Cilia through the GTPase ARL6/BBS3

The sorting of signaling receptors into and out of cilia relies on the BBSome, a complex of Bardet-Biedl syndrome (BBS) proteins, and on the intraflagellar transport (IFT) machinery. GTP loading onto the Arf-like GTPase ARL6/BBS3 drives assembly of a membrane-apposed BBSome coat that promotes cargo...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Liew, Gerald M., Ye, Fan, Nager, Andrew R., Murphy, J. Patrick, Lee, Jaclyn S., Aguiar, Mike, Breslow, David K., Gygi, Steven P., Nachury, Maxence V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255629/
https://ncbi.nlm.nih.gov/pubmed/25443296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.09.004
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