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Intraflagellar transport protein RABL5/IFT22 recruits the BBSome to the basal body through the GTPase ARL6/BBS3

Bardet-Biedl syndrome (BBS) is a ciliopathy caused by defects in the assembly or distribution of the BBSome, a conserved protein complex. The BBSome cycles via intraflagellar transport (IFT) through cilia to transport signaling proteins. How the BBSome is recruited to the basal body for binding to I...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Xue, Bin, Liu, Yan-Xia, Dong, Bin, Wingfield, Jenna L., Wu, Mingfu, Sun, Jun, Lechtreck, Karl F., Fan, Zhen-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007519/
https://ncbi.nlm.nih.gov/pubmed/31953262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901665117
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