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The CEP19-RABL2 GTPase complex binds IFT-B to initiate intraflagellar transport at the ciliary base

Highly conserved intraflagellar transport (IFT) protein complexes direct both the assembly of primary cilia and the trafficking of signaling molecules. IFT complexes initially accumulate at the base of the cilium, and periodically enter the cilium suggesting a yet identified mechanism that triggers...

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Bibliografiske detaljer
Udgivet i:Dev Cell
Main Authors: Kanie, Tomoharu, Abbott, Keene Louis, Mooney, Nancie Ann, Plowey, Edward Douglas, Demeter, Janos, Jackson, Peter Kent
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556974/
https://ncbi.nlm.nih.gov/pubmed/28625565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.05.016
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