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Structure and bioactivity of colibactin.

Colibactin is a secondary metabolite produced by certain strains of bacteria found in the human gut. The presence of colibactin-producing bacteria has been linked to colorectal cancer in humans. Colibactin was first discovered in 2006, but because it is produced in small quantities and is unstable,...

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Bibliographische Detailangaben
Veröffentlicht in:Bioorg Med Chem Lett
Hauptverfasser: Wernke, Kevin M., Xue, Mengzhao, Tirla, Alina, Kim, Chung Sub, Crawford, Jason M., Herzon, Seth B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309967/
https://ncbi.nlm.nih.gov/pubmed/32527463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127280
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