Efficacy of THN201, a Combination of Donepezil and Mefloquine, to Reverse Neurocognitive Deficits in Alzheimer’s Disease

Donepezil (DPZ) is an acetylcholinesterase inhibitor used in Alzheimer’s disease to restore cognitive functions but is endowed with limited efficacy. Recent studies pointed out the implication of astroglial networks in cognitive processes, notably via astrocyte connexins (Cxs), proteins involved in...

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Dettagli Bibliografici
Pubblicato in:Front Neurosci
Autori principali: Droguerre, Marine, Duchêne, Adeline, Picoli, Christèle, Portal, Benjamin, Lejards, Camille, Guiard, Bruno P., Meunier, Johann, Villard, Vanessa, Déglon, Nicole, Hamon, Michel, Mouthon, Franck, Charvériat, Mathieu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309601/
https://ncbi.nlm.nih.gov/pubmed/32612499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00563
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