Efficacy of THN201, a Combination of Donepezil and Mefloquine, to Reverse Neurocognitive Deficits in Alzheimer’s Disease

Donepezil (DPZ) is an acetylcholinesterase inhibitor used in Alzheimer’s disease to restore cognitive functions but is endowed with limited efficacy. Recent studies pointed out the implication of astroglial networks in cognitive processes, notably via astrocyte connexins (Cxs), proteins involved in...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Neurosci
Päätekijät: Droguerre, Marine, Duchêne, Adeline, Picoli, Christèle, Portal, Benjamin, Lejards, Camille, Guiard, Bruno P., Meunier, Johann, Villard, Vanessa, Déglon, Nicole, Hamon, Michel, Mouthon, Franck, Charvériat, Mathieu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2020
Aiheet:
Neuroscience
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309601/
https://ncbi.nlm.nih.gov/pubmed/32612499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00563
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