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Potentiation of Amitriptyline Anti-Hyperalgesic-Like Action By Astroglial Connexin 43 Inhibition in Neuropathic Rats

Antidepressants, prescribed as first line treatment of neuropathic pain, have a limited efficacy and poorly tolerated side effects. Because recent studies pointed out the implication of astroglial connexins (Cx) in both neuropathic pain and antidepressive treatment, we investigated whether their blo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jeanson, Tiffany, Duchêne, Adeline, Richard, Damien, Bourgoin, Sylvie, Picoli, Christèle, Ezan, Pascal, Mouthon, Franck, Giaume, Christian, Hamon, Michel, Charvériat, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150232/
https://ncbi.nlm.nih.gov/pubmed/27941941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38766
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