Efficacy of THN201, a Combination of Donepezil and Mefloquine, to Reverse Neurocognitive Deficits in Alzheimer’s Disease

Donepezil (DPZ) is an acetylcholinesterase inhibitor used in Alzheimer’s disease to restore cognitive functions but is endowed with limited efficacy. Recent studies pointed out the implication of astroglial networks in cognitive processes, notably via astrocyte connexins (Cxs), proteins involved in...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Droguerre, Marine, Duchêne, Adeline, Picoli, Christèle, Portal, Benjamin, Lejards, Camille, Guiard, Bruno P., Meunier, Johann, Villard, Vanessa, Déglon, Nicole, Hamon, Michel, Mouthon, Franck, Charvériat, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309601/
https://ncbi.nlm.nih.gov/pubmed/32612499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00563
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