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Signaling Inhibitors Accelerate the Conversion of mouse iPS Cells into Cancer Stem Cells in the Tumor Microenvironment

Cancer stem cells (CSCs) are a class of cancer cells characterized by self-renewal, differentiation and tumorigenic potential. We previously established a model of CSCs by culturing mouse induced pluripotent stem cells (miPSCs) for four weeks in the presence of a conditioned medium (CM) of cancer ce...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Du, Juan, Xu, Yanning, Sasada, Saki, Oo, Aung Ko Ko, Hassan, Ghmkin, Mahmud, Hafizah, Khayrani, Apriliana Cahya, Alam, Md Jahangir, Kumon, Kazuki, Uesaki, Ryo, Afify, Said M., Mansour, Hager M., Nair, Neha, Zahra, Maram H., Seno, Akimasa, Okada, Nobuhiro, Chen, Ling, Yan, Ting, Seno, Masaharu
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308356/
https://ncbi.nlm.nih.gov/pubmed/32572057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66471-2
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