Signaling Inhibitors Accelerate the Conversion of mouse iPS Cells into Cancer Stem Cells in the Tumor Microenvironment

Cancer stem cells (CSCs) are a class of cancer cells characterized by self-renewal, differentiation and tumorigenic potential. We previously established a model of CSCs by culturing mouse induced pluripotent stem cells (miPSCs) for four weeks in the presence of a conditioned medium (CM) of cancer ce...

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Publicado en:Sci Rep
Autores principales: Du, Juan, Xu, Yanning, Sasada, Saki, Oo, Aung Ko Ko, Hassan, Ghmkin, Mahmud, Hafizah, Khayrani, Apriliana Cahya, Alam, Md Jahangir, Kumon, Kazuki, Uesaki, Ryo, Afify, Said M., Mansour, Hager M., Nair, Neha, Zahra, Maram H., Seno, Akimasa, Okada, Nobuhiro, Chen, Ling, Yan, Ting, Seno, Masaharu
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308356/
https://ncbi.nlm.nih.gov/pubmed/32572057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66471-2
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