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Targeting Ovarian Cancer Cells Overexpressing CD44 with Immunoliposomes Encapsulating Glycosylated Paclitaxel

Paclitaxel (PTX) is one of the front-line drugs approved for the treatment of ovarian cancer. However, the application of PTX is limited due to the significant hydrophobicity and poor pharmacokinetics. We previously reported target-directed liposomes carrying tumor-selective conjugated antibody and...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Khayrani, Apriliana Cahya, Mahmud, Hafizah, Oo, Aung Ko Ko, Zahra, Maram H., Oze, Miharu, Du, Juan, Alam, Md Jahangir, Afify, Said M., Quora, Hagar A. Abu, Shigehiro, Tsukasa, Calle, Anna Sanchez, Okada, Nobuhiro, Seno, Akimasa, Fujita, Koki, Hamada, Hiroki, Seno, Yuhki, Mandai, Tadakatsu, Seno, Masaharu
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429518/
https://ncbi.nlm.nih.gov/pubmed/30818864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051042
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