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Mapping CRISPR spaceromes reveals vast host-specific viromes of prokaryotes

CRISPR arrays contain spacers, some of which are homologous to genome segments of viruses and other parasitic genetic elements and are employed as portion of guide RNAs to recognize and specifically inactivate the target genomes. However, the fraction of the spacers in sequenced CRISPR arrays that r...

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Dades bibliogràfiques
Publicat a:Commun Biol
Autors principals: Shmakov, Sergey A., Wolf, Yuri I., Savitskaya, Ekaterina, Severinov, Konstantin V., Koonin, Eugene V.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308287/
https://ncbi.nlm.nih.gov/pubmed/32572116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1014-1
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