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Evolution of the CRISPR-Cas adaptive immunity systems in prokaryotes: models and observations on virus–host coevolution

CRISPR-Cas is an adaptive immunity system in prokaryotes that functions via a unique mechanism which involves incorporation of foreign DNA fragments into CRISPR arrays and subsequent utilization of transcripts of these inserts (known as spacers) as guide RNAs to cleave the cognate selfish element ge...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Biosyst
Main Authors: Koonin, Eugene V., Wolf, Yuri I.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875448/
https://ncbi.nlm.nih.gov/pubmed/25238531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4mb00438h
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