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Evolution of the CRISPR-Cas adaptive immunity systems in prokaryotes: models and observations on virus–host coevolution

CRISPR-Cas is an adaptive immunity system in prokaryotes that functions via a unique mechanism which involves incorporation of foreign DNA fragments into CRISPR arrays and subsequent utilization of transcripts of these inserts (known as spacers) as guide RNAs to cleave the cognate selfish element ge...

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Bibliografische gegevens
Gepubliceerd in:Mol Biosyst
Hoofdauteurs: Koonin, Eugene V., Wolf, Yuri I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875448/
https://ncbi.nlm.nih.gov/pubmed/25238531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4mb00438h
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