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Evolution of the CRISPR-Cas adaptive immunity systems in prokaryotes: models and observations on virus–host coevolution

CRISPR-Cas is an adaptive immunity system in prokaryotes that functions via a unique mechanism which involves incorporation of foreign DNA fragments into CRISPR arrays and subsequent utilization of transcripts of these inserts (known as spacers) as guide RNAs to cleave the cognate selfish element ge...

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Bibliografiska uppgifter
I publikationen:Mol Biosyst
Huvudupphovsmän: Koonin, Eugene V., Wolf, Yuri I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875448/
https://ncbi.nlm.nih.gov/pubmed/25238531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4mb00438h
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