Duchenne muscular dystrophy hiPSC–derived myoblast drug screen identifies compounds that ameliorate disease in mdx mice

Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy. In the present study, when human induced pluripotent stem cells (hiPSCs) were differentiated into myoblasts, the myoblasts derived from DMD patient hiPSCs (DMD hiPSC–derived myoblasts) exhibited an identifiable DMD-relevant phe...

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Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Sun, Congshan, Choi, In Young, Gonzalez, Yazmin I. Rovira, Andersen, Peter, Talbot, C. Conover, Iyer, Shama R., Lovering, Richard M., Wagner, Kathryn R., Lee, Gabsang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308059/
https://ncbi.nlm.nih.gov/pubmed/32343677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134287
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