Drusen in patient-derived hiPSC-RPE models of macular dystrophies

Age-related macular degeneration (AMD) and related macular dystrophies (MDs) are a major cause of vision loss. However, the mechanisms underlying their progression remain ill-defined. This is partly due to the lack of disease models recapitulating the human pathology. Furthermore, in vivo studies ha...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Galloway, Chad A., Dalvi, Sonal, Hung, Sandy S. C., MacDonald, Leslie A., Latchney, Lisa R., Wong, Raymond C. B., Guymer, Robyn H., Mackey, David A., Williams, David S., Chung, Mina M., Gamm, David M., Pébay, Alice, Hewitt, Alex W., Singh, Ruchira
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
Sujets:
PNAS Plus
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625924/
https://ncbi.nlm.nih.gov/pubmed/28878022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710430114
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