Drusen in patient-derived hiPSC-RPE models of macular dystrophies

Age-related macular degeneration (AMD) and related macular dystrophies (MDs) are a major cause of vision loss. However, the mechanisms underlying their progression remain ill-defined. This is partly due to the lack of disease models recapitulating the human pathology. Furthermore, in vivo studies ha...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Galloway, Chad A., Dalvi, Sonal, Hung, Sandy S. C., MacDonald, Leslie A., Latchney, Lisa R., Wong, Raymond C. B., Guymer, Robyn H., Mackey, David A., Williams, David S., Chung, Mina M., Gamm, David M., Pébay, Alice, Hewitt, Alex W., Singh, Ruchira
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625924/
https://ncbi.nlm.nih.gov/pubmed/28878022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710430114
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