Drusen in patient-derived hiPSC-RPE models of macular dystrophies

Age-related macular degeneration (AMD) and related macular dystrophies (MDs) are a major cause of vision loss. However, the mechanisms underlying their progression remain ill-defined. This is partly due to the lack of disease models recapitulating the human pathology. Furthermore, in vivo studies ha...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Galloway, Chad A., Dalvi, Sonal, Hung, Sandy S. C., MacDonald, Leslie A., Latchney, Lisa R., Wong, Raymond C. B., Guymer, Robyn H., Mackey, David A., Williams, David S., Chung, Mina M., Gamm, David M., Pébay, Alice, Hewitt, Alex W., Singh, Ruchira
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625924/
https://ncbi.nlm.nih.gov/pubmed/28878022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710430114
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