Characterization of Human iPSC-RPE on a Prosthetic Bruch's Membrane Manufactured From Silk Fibroin

PURPOSE: RPE cell transplantation as a potential treatment for AMD has been extensively investigated; however, in AMD, ultrastructural damage affects both the RPE and its underlying matrix support, the Bruch's membrane (BrM). An RPE monolayer supported by a surrogate scaffold could thus provide...

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Dades bibliogràfiques
Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Galloway, Chad A., Dalvi, Sonal, Shadforth, Audra M. A., Suzuki, Shuko, Wilson, Molly, Kuai, David, Hashim, Ali, MacDonald, Leslie A., Gamm, David M., Harkin, Damien G., Singh, Ruchira
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2018
Matèries:
Retinal Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989661/
https://ncbi.nlm.nih.gov/pubmed/30025113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-23157
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