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NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure

Paternal cigarette smoke (CS) exposure is associated with increased risk of behavioral disorders and cancer in offspring, but the mechanism has not been identified. Here we use mouse models to investigate mechanisms and impacts of paternal CS exposure. We demonstrate that CS exposure induces sperm D...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Murphy, Patrick J., Guo, Jingtao, Jenkins, Timothy G., James, Emma R., Hoidal, John R., Huecksteadt, Thomas, Broberg, Dallin S., Hotaling, James M., Alonso, David F., Carrell, Douglas T., Cairns, Bradley R., Aston, Kenneth I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307791/
https://ncbi.nlm.nih.gov/pubmed/32520939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008756
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